First lady Jill Biden will also attend the meeting with the pontiff.
The U.S. Conference of Catholic Bishops this summer voted to draft new guidance on the Eucharist, or Holy Communion, that could result in denying the sacrament to politicians who support abortion legislation.
Francis, who would have to approve the new guidance, has been mum on whether politicians should be denied Communion because of their abortion stance.
When asked in September if he supported the ban, the pope warned bishops not to let politics enter into questions about receiving Communion, but repeated that abortion was “homicide” and the Eucharist cannot be given to anyone who is not “in communion” with the church, though he declined to say if pro-abortion politicians were out of Communion.
The president will then travel to Glasgow Scotland, for the United Nations climate conference known as COP26, where he is slated to announce “key actions” on fighting climate change.